Isotopically Labeled Compounds
Medchemexpress LLC D-Glucose-d1 | 56570-89-9 | 99.9% | 5 MG
D-Glucose-d is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. It is a carbohydrate sweetener and a critical component of general metabolism, serving as a critical signaling molecule. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, primarily as tracers for quantitation during the drug development process. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs. The product is for research use only.
- Application as a tracer.
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium labeling provides a means for tracing during drug development.
Medchemexpress LLC D-Glucose-d12-1 | 89798-27-6 | 99.4% | 50 MG
D-Glucose-d12-1 is a deuterium-labeled D-Glucose. It is a monosaccharide, a crucial carbohydrate in biology, a carbohydrate sweetener, and a vital component of general metabolism. It also serves as a critical signaling molecule related to cellular metabolic status and biotic and abiotic stress responses.
- Can be used as a tracer.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes into drug molecules for quantitation during drug development.
- Deuteration can potentially affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Lercanidipine-d3 hydrochloride | 1189954-18-4 | 98.14% | 1 MG
Lercanidipine-d3 hydrochloride is the deuterium-labeled form of Lercanidipine, a lipophilic third-generation dihydropyridine-calcium channel blocker (DHP-CCB). It offers long-lasting antihypertensive action and reno-protective effects. Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules primarily as tracers for quantitation during drug development. Deuteration can impact the pharmacokinetic and metabolic profiles of drugs.
- Functions as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Nizatidine-d3 | 1246833-99-7 | 98.8% | 5 MG
Nizatidine-d3 is the deuterium-labeled form of Nizatidine, a potent and orally active histamine H2 receptor antagonist. It is used in the research of stomach and intestinal ulcers by decreasing gastric acid secretion and preventing ulcer recurrence. Its deuterium labeling makes it valuable as a tracer and internal standard for quantitative analysis in drug development.
- Deuterium labeled Nizatidine
- Potent and orally active histamine H2 receptor antagonist
- Used for research of stomach and intestines ulcers
- Decreases secretion of gastric acid
- Prevents ulcers from returning after healing in animal models
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC D-Glucose-13C-3 | 105931-74-6 | 99.7% | 250 MG
D-Glucose-13C-3 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and a critical component of general metabolism, serving as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Ethylmalonic acid-d5 | 66311-22-6 | 98.1% | 137.15 | 1 MG
Ethylmalonic acid-d5 is a deuterium labeled short-chain organic dicarboxylic acid. It synergistically induces mitochondrial permeability transition with Ca2+, inhibits Mi-CK, and disrupts mitochondrial energy metabolism. This compound can be used in the research of SCADD, EE, and other genetic metabolic diseases characterized by EMA accumulation.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuterium labeled compound for pharmacokinetic and metabolic studies
- Inhibits mitochondrial creatine kinase activity
- Disrupts mitochondrial energy metabolism
Medchemexpress LLC Sulfadimethoxine-d6 | 73068-02-7 | 99.0% | 1 MG
Sulfadimethoxine-d6 is a deuterium-labeled version of Sulfadimethoxine, a sulfonamide antibiotic used to treat various infections. It is a stable isotope-labeled compound primarily used as a tracer and internal standard in quantitative analysis.
- Deuterium-labeled compound
- Used as a tracer
- Internal standard for NMR, GC-MS, or LC-MS analysis
- Intended for research use only
- Stable under recommended storage conditions
- Not classified as a hazardous substance or mixture
Medchemexpress LLC Ketotifen-d3 fumarate | 1795138-23-6 | 99.2% | 5 MG
Ketotifen-d3 fumarate is a deuterium labeled version of Ketotifen fumarate, a second-generation noncompetitive H1-antihistamine and mast cell stabilizer. It is primarily used for research purposes, including as a tracer and internal standard for quantitative analysis methods like NMR, GC-MS, or LC-MS.
- Deuterium labeled version for research applications
- Functions as a noncompetitive H1-antihistamine
- Acts as a mast cell stabilizer
- Can be used as a tracer
- Serves as an internal standard for quantitative analysis
- Suitable for NMR, GC-MS, or LC-MS applications
Medchemexpress LLC D-Glucose-d1-4 | 106032-61-5 | 98.0% | 50 MG
D-Glucose-d1-4 is the deuterium labeled D-Glucose, a monosaccharide and important carbohydrate in biology. It serves as a carbohydrate sweetener and plays critical roles in general metabolism, cellular metabolic status, and stress response. This compound is for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes of hydrogen and carbon
- Potential to affect the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Lactic acid-d3 sodium | 1219802-24-0 | 98% | 5 MG
Lactic acid-d3 sodium is the deuterium labeled form of Lactic acid sodium, an HCAR1 activator and epigenetic modulator. It plays a role as a glycolysis end-product, bridging glycolysis and oxidative phosphorylation. This compound is also recognized as an oncometabolite with an immune protective role in anti-tumor immunity and possesses antimicrobial activity, making it suitable as a food preservative.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Sulfadoxine-d4 | 1330266-05-1 | 98.0% | 1 MG
Sulfadoxine-d4 is the deuterium labeled Sulfadoxine, a long-acting sulfonamide. It is commonly used in combination with other agents for respiratory, urinary tract, and malarial infections, and has shown to inhibit HIV replication in peripheral blood mononuclear cells.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cambridge Isotope Laboratories L-Phenylalanine (Ring-D5) | 56253-90-8 | MFCD00144664 | 1 g
L-Phenylalanine (Ring-D5) | Purity: 98% | Mol Wt: 170.22 | 56253-90-8 | MFCD00144664 | 1 g
Medchemexpress LLC Monomethyl auristatin E-d8 | 2070009-72-0 | MFCD28386277 | 99.3% | 726.03 | C39H59D8N5O7 | 10 MG
MMAE-d8 is a deuterated isotopologue of monomethyl auristatin E, a potent mitotic inhibitor that disrupts microtubule dynamics. The deuterium-labeled compound is designed for use as an analytical standard, tracer, or internal standard in antibody-drug conjugate research, mass spectrometry, and pharmacokinetic studies. Supplied as a high-purity solid for laboratory use.
- Deuterated isotopologue for analytical and tracer applications.
- Potent tubulin inhibitor useful as an ADC payload reference.
- High reported purity suitable for sensitive assays.
- Available in small milligram pack sizes for research workflows.
- Supplied as a stable solid for accurate dosing and handling.
Medchemexpress LLC Oxaprozin-d4 | 2070015-11-9 | 99.1% | 1 MG
Oxaprozin-d4 is the deuterium labeled Oxaprozin, functioning as a non-steroidal anti-inflammatory agent (NSAID).
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Captopril-d3 | 1356383-38-4 | 100 UG
Captopril-d3 is deuterium labeled Captopril. It is an antihypertensive agent and a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM). It has been widely used in research for hypertension and congestive heart failure. Captopril-d3 also acts as a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC50 of 7.9 μM. It is for research use only.
- Can be used as a tracer for drug development
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration affects pharmacokinetic and metabolic profiles of drugs
- Molecular weight: 220.30
- Chemical formula: C9H12D3NO3S